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Media Advisory
Tuesday, September 17, 2024
NIH releases mpox research agenda
Plan will advance knowledge of virus biology to improve detection, treatment and prevention.
What
As part of the U.S. government response to the , the National Institutes of Health’s (NIH) National Institute of Allergy and Infectious Diseases (NIAID) has . The NIAID mpox research agenda focuses on four key objectives: increasing knowledge about the biology of all clades—also known as strains—of the virus that causes mpox, including how the virus is transmitted and how people’s immune systems respond to it; evaluating dosing regimens of current vaccines to stretch the vaccine supply and developing novel vaccine concepts; advancing existing and novel treatments, including antivirals and monoclonal antibodies; and supporting strategies for detecting the virus to facilitate clinical care and epidemiological surveillance.Â
The first human case of mpox was recorded in 1970 in the Democratic Republic of the Congo. The disease is endemic in central and western Africa. Two types of the virus that causes mpox have been identified: Clade I is endemic in Central Africa and can cause severe illness. Clade II, endemic in West Africa, tends to result in milder illness and . People with compromised immune systems, children, and people who are pregnant are especially vulnerable to severe mpox regardless of the virus clade.
NIAID continues to collaborate closely with U.S. and international partners to reduce the impact of the current mpox outbreak and safeguard public health globally. NIAID will leverage both its domestic and international research infrastructures to achieve the Institute’s research objectives.
Who
NIAID Director Jeanne M. Marrazzo, M.D., M.P.H., is available to discuss the institute’s mpox research agenda. of her summarizing the priorities. .
NIAID conducts and supports research—ar Â鶹´«Ã½, throughout the United States, and worldwide—to study the causes of infectious and immune-mediated diseases, and to develop better means of preventing, diagnosing and treating these illnesses. News releases, fact sheets and other NIAID-related materials are available on the .
About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. Â鶹´«Ã½ is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information abour Â鶹´«Ã½ and its programs, visit www.nih.gov.
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